Risk Of ED

Heart Medications Don’t Raise The Risk Of ED

There have been studies that drugs taken to lower blood pressure or cholesterol can lead to erectile dysfunction issues. However, that’s not likely, a new Canadian study suggests.


The randomized, controlled trial, a substudy of the Heart Outcomes Prevention Evaluation-3 (HOPE-3) trial, focused on two medications: candesartan with hydrochlorothiazide (HCTZ), a combination drug that lowers blood pressure and rosuvastatin (a statin that reduces cholesterol).


“This Canadian study involved approx. 2,000 men who’re taking a cholesterol-lowering statin drug, a blood pressure-lowering medication, or both. The average age of men was 62 years.”


To measure erections, the men completed the International Index of Erectile Function (IIEF) questionnaire at the initial stage of the study and then again at a follow-up point (several years later). The follow-up duration for the study was almost 6 years.


The samples of both the groups were taken for comparison. The researchers did not see any significant changes between the baseline and follow-up evaluations and concluded that the two drugs, used alone or together, did not improve or worsen erectile function.


According to the Dr. Philip Joseph, an Assistant Professor of Medicine at McMaster University in Hamilton, Ontario, Canada, “By lowering critical cardiac risk factors and taking these medications, there is a little impact on changes in erectile function.” This means there is no link between the between the drugs and the development of erectile dysfunction.


According to him, “The prior studies that pointed to high blood pressure and high cholesterol as being tied to erectile dysfunction, but there’s been much less study into whether heart medicines affected that risk – either for good or bad.”


The new study suggests that heart drugs don’t increase the risk of erectile dysfunction in heart patients. Moreover, by reducing critically important cardiac risk factors taking heart medicines has little impact on changes in erectile function.


Joseph believes the findings should provide clarity for heart patients dealing with erectile dysfunction.

What Heart Patients Can Do To Treat ED?

Heart patients dealing with ED issues must visit their health care providers and talk about their health concerns. Their healthcare professional may recommend Sildenafil prescription or generic Viagra coupon to treat the ED issues. Just make sure to take the ED medicines as per the doctors’ recommendation.


Canadian Journal of Cardiology

Joseph, Philip MD, et al. “Long-term Effects of Statins, Blood Pressure-Lowering, and Both on Erectile Function in Persons at Intermediate Risk for Cardiovascular Disease: A Substudy of the Heart Outcomes Prevention Evaluation-3 (HOPE-3) Randomized Controlled Trial”
(Abstract. January 2018)


Mancini, G.B. John MD, FRCPC, FACC
“Cardiovascular Risk Reduction and Male Sexual Health: No Free Ride” (Editorial. January 2018)

“Medications to treat cardiovascular risk factors do not impact erectile function” (Press release. January 29, 2018)

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